The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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Spatial composition facilitates cooperation inside a social Problem: empirical evidence from a bacterial Local community
Our team studies bacterial mobile division and it is aiming to constitute a ‘base up biology’ in artificial cells which can autonomously divide. Our main desire lies in mobile division, chromatin construction, and spatial Manage.
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
Because 2000, Dekker has shifted the leading focus of his operate to biophysics in which he scientific tests the properties of single biomolecules and cells using the instruments of nanotechnology. This change of discipline was pushed by his fascination with the outstanding performing of Organic molecular structures, along with with the extensive-term perspective that lots of appealing discoveries is usually expected On this discipline.[five] Latest strains of research in his biophysics group are in the areas of:[6]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initially ever analyze on the dynamics DNA supercoils and the discovery of supercoil hopping
Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: rapidly electron relay to redox enzymes and zeptomole protein-film voltammetry
You're a Christian. If you might make such a artificial cell, would you be a person phase closer to God, or would the purpose of God have diminished fairly again?
Atomic force microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative style
Being familiar with essential procedures regulating the spatial and dynamic organisation of your DNA in Are living cells.
Dekker started off his study on single carbon nanotubes in 1993 when he arrange a completely new line of exploration to review electrical transport by means of single organic molecules involving nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was reached inside a collaboration Using the team of Nobel laureate Richard Smalley. STM and nanolithography tactics were utilized to show that these nanotubes are quantum wires at The one-molecule degree, with outstanding Bodily properties.
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Cees Dekker is Distinguished College Professor at TU Delft. Properly trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His current investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow on the APS as well as the IOP.
2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin in the electrophoretic power on DNA in nanopores; identified a substantial velocity improve of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of noise in carbon nanotubes in liquid
Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, https://www.ceesdekker.net as well as a 3D rendering of your motion of the DNA rod is shown.